diff --git a/src/osal.h b/src/osal.h
index f708864b..8a34915d 100644
--- a/src/osal.h
+++ b/src/osal.h
@@ -118,9 +118,11 @@ typedef pthread_mutex_t mdbx_fastmutex_t;
 #endif
 
 #if !defined(UNALIGNED_OK)
-#if defined(__i386) || defined(__x86_64__) || defined(_M_IX86) ||              \
-    defined(_M_X64) || defined(i386) || defined(_X86_) || defined(__i386__) || \
-    defined(_X86_64_) || defined(__ARM_FEATURE_UNALIGNED) || defined(__e2k__)
+#if (defined(__i386) || defined(__x86_64__) || defined(_M_IX86) ||             \
+     defined(_M_X64) || defined(i386) || defined(_X86_) ||                     \
+     defined(__i386__) || defined(_X86_64_) ||                                 \
+     defined(__ARM_FEATURE_UNALIGNED) || defined(__e2k__)) &&                  \
+    !defined(__ALIGNED__)
 #define UNALIGNED_OK 1
 #else
 #define UNALIGNED_OK 0